My dog goes to daycare 5 days per week while I'm at work, running around playing with dozens of other dogs on around 5 acres, with I believe about three to five humans around to supervise.
When I first got him and I was getting daycare set up, he was home alone for about 12 hours a few times, but he was good and to this day has still never peed in the house even once.
He did shred a down comforter once though. That was about a year ago and I'm still finding feathers.